Monday, February 25, 2013

Sickle Cell Anemia

Sickle Cell Anemia - what is anemia -

Red blood cells with normal hemoglobin                  Red blood cells with sickle cell hemoglobin

sickle cell hemoglobin. red blood cells red blood cells anemia

  1. Charged Objects Like to be Surrounded by Water

A piece of charged Saran Wrap is attracted to          … but not to olive oil
water …

  1. A piece of charged Saran Wrap is attracted to water …

Charged Molecules are More Soluble in Water

Sickle Cell Patient 
  •  36 year old black male diagnosed with sickle cell anemia at age 2
  •  Formerly had 1 painful crisis each year, but recently has had 3 - 4 per year 
  • Last October, acute chest syndrome Æ coumadin anticoagulation 
  •  Bone infarcts in arms, legs, and hip.  Rods placed in both arms and legs 

Treatment

  • Hydration
  • O2
  • Hydroxyurea Æ Induces fetal hemoglobin
  • Folate Æ Prevent aplastic crisis due to folate deficiency
  • Pain medication
  • Exchange transfusion

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